Rejuvenative PDRN-NE Ampoule - Face Serum

THE NEXT LEVEL IN
CELLULAR SKINCARE

NANO-EMULSION
ADVANCED DELIVERY FOR
VISIBLE REVITALIZATION

A high-performance skin-conditioning program featuring 1% intact salmon-derived PDRN delivered through a proprietary nano-emulsion delivery system to visibly lift, firm, smooth, and refine the complexion.

Rejuvenative PDRN-NE Ampoule is a four-week, intensive skin-conditioning program powered by intact Sodium DNA (PDRN) at a clinically optimized 1% concentration. Each set includes four 5ml vials, designed for weekly use to help improve the appearance of skin elasticity, firmness, tone, and smoothness, leaving the complexion looking more refined and revitalized.

This advanced serum-emulsion absorbs softly into the skin while providing a comforting veil of moisture—ideal for dry, mature, or fatigued skin that needs visible revitalization and support.

PDRN (Sodium DNA) is a naturally occurring DNA-derived ingredient to help support skin vitality and improve the appearance of overall skin quality. However, because PDRN is a large molecule, standard serums cannot deliver it effectively.

VENN’s Nano-Emulsion (NE) technology encapsulates intact PDRN in sub-200 nm droplets that protect the molecule, enhance absorption, and release gradually to support visible revitalization.

The formula is further strengthened with a powerful network of peptides and vegan EGF, 17 amino acids, niosome-encapsulated panthenol, a multi-layer hydration system, and barrier-reinforcing ingredients including ectoin, ceramide NP, and glutathione. Together, they help improve the look of firmness, elasticity, tone, and radiance while supporting a smoother, healthier-looking complexion.

The treatment’s translucent, faint-blue hue is not from dyes—it is a natural result of the Tyndall effect, confirming true nano-scale dispersion.

Clinical results (based on a 2-week in-vivo clinical study, 20 subjects):
+ Improved surface and deep skin elasticity
+ Visible lifting of cheeks, chin, nasolabial folds, and mouth corners
+ Reduced appearance of wrinkles
+ Reduced visible redness
+ Diminished superficial dark spots and hyperpigmentation
+ Improved look of deep pigmentation

Consumer perception (20 subjects, 2 weeks, morning and evening use):
+ 100% agreed skin felt more elastic, lifted, soothed, healthier, and younger
+ 100% agreed skin tone looked improved and more even; pores looked smaller; skin looked brighter
+ 95% agreed wrinkles around the eyes looked reduced

Cruelty free. Leaping Bunny certified. None of our products, including the ingredients, are tested on animals.

Directions: Use one 5ml vial per week as part of a four-week intensive skin-conditioning program. Apply 6–9 drops per use, gently squeezing the applicator to dispense the serum into your palm. Using your fingertips, pat the serum evenly across freshly cleansed skin, morning and night. Follow with your preferred VENN moisturizer to complete your routine.

This program may be repeated every 2–3 months or used as a daily serum for ongoing skin maintenance.

Caution: For topical, external use only. Do not use on damaged or irritated skin. Do not use if you are allergic to any of the ingredients. Discontinue use if irritation or rash occurs and consult a physician. Avoid direct contact with eyes. Store in a cool, dry place away from heat and direct sunlight. Keep out of reach of children.

WHAT IS PDRN?

PDRN (Sodium DNA) is a DNA-derived ingredient valued for helping improve the appearance of skin elasticity, firmness, and overall skin vitality. Due to its large molecular structure, incorporating PDRN into topical skincare requires thoughtful formulation. In our Rejuvenative PDRN-NE Ampoule, we use high-purity PDRN sourced from salmon-derived DNA and formulate it with our Nano-Emulsion (NE) technology to help ensure even dispersion and optimal cosmetic performance on the skin. This advanced formulation helps refine the appearance of skin texture, leaving the complexion looking smoother, firmer, and healthier-looking.

OUR PDRN ORIGIN

Our PDRN is sourced from highly purified salmon sperm DNA, chosen for its exceptional purity, structural similarity to human DNA, and ability to remain intact for optimal performance.

While many formulas rely on hydrolyzed or plant-derived DNA fragments—which mainly act as humectants—our use of intact, long-chain PDRN preserves the molecule’s natural integrity and enables superior performance when paired with our nano-emulsion delivery system.

PDRN VS. EXOSOME: WHEN TO USE EACH

Both ampoules are designed to help improve the appearance of skin quality, while addressing different skin concerns through distinct formulation approaches.

Rejuvenative PDRN-NE Ampoule is formulated to help enhance the appearance of skin comfort, resilience, and smoothness. It helps visibly refine skin texture and support a well-conditioned, moisturized look, with noticeable improvements in the appearance of elasticity and suppleness. Its richer emulsion texture makes it especially well-suited for dry, mature, depleted, or fatigued-looking skin in need of enhanced comfort and firmness-looking results.

Regenerative 10B-EXO EGF Ampoule is formulated to help improve the appearance of skin texture, elasticity, and tone while promoting a calm, balanced-looking complexion. Its lightweight, fast-absorbing texture makes it an excellent option for combination, stressed, sensitive-looking, or post-procedure skin, helping skin appear smoother, clearer, and more refined.